Based on evidence from research on the receptors’ function in the brain and the drugs that can activate or inhibit them, the authors propose possible mechanisms by which GABA-modulating ...

A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors’ importance in depression and potential as therapeutic targets.

When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. This can help with feelings of anxiety, stress, and fear. It may also help to prevent seizures.

"All of these drugs target GABA-A receptors, and we had some clues that these receptors might be affected in DM, because of years of reports on post-operative anesthesia complications," says ...

GABA is a naturally occurring amino acid that functions as an inhibitory neurotransmitter. It attaches to nerve receptors in the brain and changes its ability to take in and send signals.

A large body of work, ranging from biochemical to genetic studies, points to the importance of certain GABA receptors in mediating the effects of alcoholism in the central nervous system.

Final results demonstrate target engagement of GRX-917 via dose-related activation of quantitative electroencephalography (qEEG) frontal beta power, a biomarker for GABA-A receptor-associated ...

"All of these drugs target GABA-A receptors, and we had some clues that these receptors might be affected in DM, because of years of reports on post-operative anesthesia complications," says ...