We investigated role of the folate–homocysteine metabolic pathway in the etiology of attention-deficit hyperactivity disorder (ADHD) due to its importance in maintaining DNA integrity as well as ...

"We are very excited by these findings because they reveal the regulation of folate metabolism as a common shared mechanism that affects several different pathways of longevity and is conserved in ...

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-21903-z Cite This Page : ...

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-23856-9 Cite This Page : ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

SARS-CoV-2 hijacks two key metabolic pathways to rapidly replicate in host cells Blocking folate metabolism with oral, prophylactic drugs could reduce viral replication in infected cells ...

Many common drugs induce megaloblastic anemia by interfering with folate or vitamin B12 absorption, altering B12 metabolism, or blocking pathways in which these vitamins play a role. Supplements to ...

Technion researchers discover new pathway for attacking cancer cells ... findings that have been published in Cell Metabolism. The folate cycle is a process essential to DNA and RNA production.

Since methylfolate is further along the metabolic pathway than folinic acid, the risks of methylfolate may be lower. ... “Folate” refers in general to folic acid and its various metabolites.

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

When SARS-CoV-2, the virus that causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell's existing metabolic machinery. The infected cells churn out thousands of ...