Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

Several metabolites related to the nicotinamide adenine dinucleotide (NAD +) pathway showed significantly decreased abundance in CLE skin. An improved understanding of the metabolic pathways involved ...

In this study, we demonstrated that ASFV pA151R negatively regulated type I IFN production. Ectopic expression of pA151R dramatically inhibited K63-linked polyubiquitination and Ser172 phosphorylation ...

Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School of Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan ...

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States ...

Celery, a key vegetable in the Apiaceae family, is widely valued for its nutrition and medicinal uses. It is commonly categorized into three varieties: A. graveolens var. dulce (common celery ...

We found that UA dinucleotides and UA-rich motifs are the most prominent destabilizing element. Gain of UA dinucleotide outlined mutant UTRs with reduced stability. Studies on endogenous transcripts ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...