Get Instant Summarized Text (Gist) Enhancing T-cell function in cancer involves targeting metabolic pathways and immune checkpoints. Blocking A2BR stabilizes GSH and GPX4, reducing T-cell ...

Fighting Cancer Without Fighting: Scientists Switch Tumor Cells Back to Healthy Ones at ‘Critical’ Moment. By. Andy Corbley - Feb 11, 2025.

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces.

A new way to grow T cells in the lab enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media. The findings&nbsp ...

Common forms of cell therapy that use T cells—the immune system’s soldiers that fight infections and cancers—include chimeric antigen receptor T cell (CAR-T), which are T cells modified to better ...

Using a technology called cellular reprogramming, the team transformed tumor cells in mice into a type of immune cell called cDC1 cells. These cells are master regulators of the immune system. They’re ...

T Cell Exhaustion and Novel Therapies. Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell ...

Serendipity reveals new method to fight cancer with T cells. ScienceDaily. Retrieved May 17, 2025 from www.sciencedaily.com / releases / 2024 / 07 / 240702135542.htm. University of Wisconsin-Madison.

Graphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101249 ...

Natural killer (NK) cell destroying a cancer cell. [Marci Klapczynski/Getty Images] Fasting, many diet gurus say, can help you lose weight and improve your overall health.

Cell-based immunotherapy uses the patient’s own immune cells to target and kill cancer cells in a specific manner. Lymphocytes called T cells are mainly used for this type of therapy, and to target ...

Fighting cancer with artificial cells that are capable of detecting and treating it. This is the dual objective of a research team of the Department of Cellular, Computational and Integrative ...