Limited penetration depth into tumor tissues continues to hinder the development of nanotherapeutics for cancer treatment. A ...

Ferroptosis is a type of iron-dependent programmed cell death implicated in cancer, and targeting the ferroptosis pathway could be a therapeutic strategy to improve clinical outcomes.

A novel self-propelled ferroptosis nanoinducer developed by Southern Medical University was able to achieve deeper ...

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular ...

From the research, it was found that ferroptosis may be a key mechanism to reverse treatment tolerance. ‘Nearly half of all cancers worldwide are digestive tract tumors. #cancer # ...

French researchers have developed phospholipid degraders that trigger iron-catalyzed cell death in aggressive cancers like pancreatic tumors and sarcomas.

Since refractory and metastatic cancers are highly susceptible to ferroptosis, sensitizing cancer cells to ferroptosis through FSP1 inhibition holds great potential for new anticancer drugs.

Their findings, published in Breast Cancer Research and Treatment, demonstrate the role of activators of ferroptosis in overcoming acquired resistance to FOXM1 inhibitors. Drug resistance poses a ...

By subjecting cancer cells to this new foe, the team was able to kill them off through a recently discovered mechanism known as ferroptosis, a type of programmed cell death that could also have ...