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2 天
News-Medical.Net on MSNTargeting IGF2BP1 offers a new approach to cancer therapyThe RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumor proliferation, ...
核因子E2相关因子 2(Nrf2)是细胞内重要的转录因子,在调节氧化应激、炎症反应及细胞代谢等多种生理过程中发挥关键作用。ML385(AbMole,M8692)作为一种特异性的Nrf2抑制剂,在科研领域受到广泛关注。它能够与 Nrf2 ...
4 天
News Medical on MSNNeurons use RNA fragments to fight back against botox damageScientists have discovered that neurons exposed to Botox (botulinum toxin A) don't just survive—they fight back.
The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumor proliferation, ...
Scientists have developed a tool that can predict how bowel cancer adapts to treatment – helping researchers to design new personalized drugs that will keep patients living well for longer.
铁死亡作为程序性细胞死亡的一种,自2012年被Dixon等人提出以来[1],相关研究呈指数级增长。最近,一项发表在《Nature》杂志上的文章再次吸引了大家的目光,它揭示了溶酶体铁在铁死亡中的关键作用,并成功开发出一种名为Fento-1的小分子化合物 ...
【导读】雄激素受体信号抑制剂(ARSIs)已在转移性前列腺癌中显示出生存获益。6月19日,上海中医药大学/安徽医科大学研究人员合作共同在期刊《Advanced Science》上发表了题为“Ezetimibe Engineered L14-8 ...
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