Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at ...

Our work contributes with new inhibitors that have structural diversity among themselves and with respect ... Moreover, ...

Our work contributes to new inhibitors that have structural diversity ... Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated ...

Specialists from Mari State University, as part of an international team, have developed an innovative compound capable of combating a ...

The study also found that ferroptosis inhibitors like liproxstatin-1 not only halt ferroptosis but also reduce necroptosis, and necroptosis inhibitors such as necrostatin-1 show reciprocal effects.

Notably, inhibiting HMOX1 with the specific inhibitor Znpp significantly reduced osteocyte death and preserved bone integrity, whereas the classical ferroptosis inhibitor, Fer-1, had a lesser effect.

The study also found that ferroptosis inhibitors like Liproxstatin-1 not only halt ferroptosis but also reduce necroptosis, ...