Background and aims: Ferroptosis, a novel concept of programmed cell death proposed in 2012, in kidney disease, has garnered significant attention based on evidence of abnormal iron deposition and ...

Ferroptosis is associated with various diseases, but the relationship with diabetic retinopathy(DR) is less studied. DR is one of the complications of diabetes mellitus and has a severe impact on ...

Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...

Department of Chemistry, Chemistry of Life Processes Institute, and Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois 60208, United States Department of Chemistry, ...

Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...

They found in the FECD samples the presence of certain genes associated with the disease and followed the path by which these genes led to ferroptosis. They also found through experiments that ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

高度近视在全球的患病率呈上升趋势，已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症，发病年龄比年龄相关性白内障更早，严重影响患者工作期间的生活质量。由于晶状体核通常较硬，HMC 的手术干预难度较大，因此深入了解其发病机制对开发潜在治疗方法至关重要。

Aerobic exercise may significantly reduce Alzheimer's disease markers, with studies showing up to 76% decreases in harmful ...