The bile salt, nuclear farnesoid X receptor (FXR), was recently implicated in intestinal antibacterial defence and barrier function. The aim of this study was to investigate the therapeutic potential ...

The orphan nuclear receptor NR0B2 was reported to suppress liver cancer development in a mouse model, and its expression levels were reduced in liver cancer tissues and cell lines due to ...

Nuclear hormone receptor NR4A1 is also required for the effect of isoalloLCA on Treg cells. In addition, a distinct Treg population expressing the transcriptional factor RORγ is also induced in the ...

Immune markers were measured by SARS-CoV-2 surrogate virus neutralisation test and spike receptor-binding domain IgG ELISA. Conclusion Our study has identified specific gut microbiota markers in ...

dDepartment of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan eLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for ...