SAVANNAH Phase II trial demonstrated high and durable response rates with savolitinib plus TAGRISSO® in MET-high lung cancer, representing a ...

This fundamental article significantly advances our understanding of FGF signalling, and in particular, highlights the complex modifications affecting this pathway. The evidence for the authors' ...

Researchers have found in a new study that maternal inflammatory proteins during pregnancy are associated with a higher risk ...

A report by the Future Governance Forum (FGF) calls for a joined-up plan to deliver local digital government, bringing the sector together through a collaborative approach.

FGF-8 is a member of the fibroblast growth factor family, originally identified as essential for the androgen-dependent growth of mouse mammary carcinoma cells. In mice, alternative splicing of ...

Mechanism of acquired resistance were assessed by: (1) role of T-ICs by in vitro sphere formation and in vivo tumourigenesis assays using NOD/SCID mice, (2) activation of alternative signalling ...

USA/China-based SciClone Pharmaceuticals has entered into a license agreement with Japan’s Eisai for the latter’s fibroblast growth factor (FGF) receptor selective tyrosine kinase inhibitor ...

Chinese-based Innovent Biologics and HUTCHMED are eyeing approval for their cancer combination after a joint Phase II/III ...

Our study has demonstrated the clinical relevance of such an interaction between the FGF and TGF-β superfamilies in vivo. As it is becoming evident that activin A is essential for the ...