Our understanding of cardiac aging, and aging in general, is limited. However, recent studies of age-related decline and its prevention through interventions like exercise have revealed novel ...

Guangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Basic Research Center of Excellence for Precise ...

Apr. 7, 2022 — Frontotemporal dementia patients with extrapyramidal symptoms have brainstem atrophy and reduced metabolism in certain areas of the brain significantly more often than patients ...

Both Vertex and Eli Lilly are entering the non-opioid pain management market, targeting the promising $20B+ opportunity. Vertex's Journavx, targeting NaV1.8, is FDA-approved and shows opioid-level ...

The study's key findings indicate that among residents receiving antipsychotic drugs (APDs), 5.6% were diagnosed with extrapyramidal syndrome (EPS), a term encompassing drug-induced movement ...

The study revealed that many residents are misdiagnosed with extrapyramidal syndrome, which could lead to inappropriate treatment options and illustrates potential deficiencies in patient ...

FANCM is crucial in genome maintenance, functioning in the Fanconi anemia (FA) pathway, alternative lengthening of telomeres (ALT), and replication fork protection. FANCM recognizes branched DNA ...

The study is solid and further in vivo evidence on how target factors participate in the occurrence of placental structural disorders and diseases through potential downstream pathways will be ...

Here, we demonstrate that inhibition of the p38 MAPK-MK2 signaling pathway sensitizes cancer cells to MTA treatment. We utilize CMPD1, a dual-target inhibitor, to concurrently suppress the p38-MK2 ...

We show that leucophores share pathways with other pigment cells but possess distinct mechanisms for uric acid biosynthesis and storage. Structural studies reveal star-like fibrous structures in ...