HLA molecules present a snapshot of the human proteome on the cell surface, rendering intracellular antigens accessible for various cancer immunotherapies. While many publicly available ...

DL has the ability to automatically extract big data and process it, which has revolutionized areas such as image classification, neural language processing, and audio/video analysis. AI application ...

Surface antigen expression requires proper intracellular protein maturation and trafficking. Interestingly, CD81, a chaperone protein regulating CD19 processing from the endoplasmic reticulum (ER) and ...

The presence of an unusually long extracellular membrane-proximal domain in membrane IgE may also determine its ability to act as an antigen receptor ... short (N-terminal) intracellular sequence ...

High-speed atomic force microscopy (HS-AFM) reveals nanoscale differences in small extracellular vesicles (sEVs), improving biomarker profiling for cancer and other diseases.

Institute of Chemical Technologies and Analytics, TU Wien, 1060 Vienna, Austria Christian Doppler Laboratory for Advanced Mid-Infrared Laser Spectroscopy in (Bio-)Process Analytics, TU Wien, 1060 ...

Tumor antigens are captured and displayed by antigen processing and presentation machinery (APM) on the cell surface by HLA-I, making it possible for CD8 + T cells to eliminate cancer cells.

FcRn regulates IgG function in innate and adaptive immune activities associated with professional antigen-presenting ... allows internalization into intracellular acidic vesicles.

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Nanomedicine. 2012;7(8):1253-1271. Liposomes Liposomes are self-assembled artificial vesicles developed from amphiphilic phospholipids. These vesicles consist of a spherical bilayer structure ...