However, two papers by Stern and colleagues 1,2 now indicate that mouse immature dendritic cells are also able to bypass the antigen-internalization stage by processing antigens extracellularly ...

Before an antigen can be presented by MHC molecules, it must undergo a process called antigen processing. Antigen processing ... compartments depending on the type of antigen: Intracellular antigens, ...

MHC Class I and MHC Class II Antigen Processing Pathways ... which are primarily extracellular. Viral infections are primarily intracellular and viruses require the host cellular machinery to ...