This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

In general, small molecules have better access to intracellular and extravascular ... into cell surface glycans by means of promiscuous enzymes in the biosynthetic pathways of these biopolymers.

Aggressive repletion with isotonic saline expands the extracellular volume and stabilizes cardiovascular functions (15 ... myocardial infarction, a rise in pancreatic enzymes with or without acute ...

Above 105 F many body enzymes become denatured and chemical reactions cannot take place leading ... Pathophysiology of Tissue Freezing - As tissue begins to freeze, ice crystals are formed within the ...