In the United States, nearly three million adults 18 years and older reported having active epilepsy during 2021 and 2022.

This study offers a valuable treatment of how the population of excitatory and inhibitory neurons integrates principles of energy efficiency in their coding strategies. The convincing analysis ...

Unlike most prior work using a similar setup, the network includes separate populations of excitatory and inhibitory neurons. The authors show that the optimised connectivity has a like-to-like ...

When Disney Channel star Cameron Boyce died in 2019, his death was ruled a sudden unexpected death in epilepsy, otherwise ...

Neuropilin2 controls migration of inhibitory neurons as well as the formation and maintenance of synaptic connections in excitatory neurons—two crucial components of brain activity. A study led ...

A Columbia-led study uncovers how gliomas cause seizures and cognitive impairments by disrupting brain activity. Using ...

Researchers found that random brain fluctuations actually strengthen memory by stabilizing neural activity over time. The ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

However, the molecular composition of their synapses remains largely uncharacterized. Here, we dissect the protein composition of the excitatory postsynaptic compartment of mouse L5 neurons in intact ...