Here, we report the synthesis of a functional 272,871-base pair designer eukaryotic chromosome, synIII, which is based on the 316,617-base pair native Saccharomyces cerevisiae chromosome III. Changes ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

The molecular insights we gain will help us better understand, and ideally treat, human diseases such as cancer. Telomeres are nucleoprotein caps that protect the ends of eukaryotic chromosomes from ...

Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, and ‡ Chromosome Engineering Research Center, Tottori University, 683-8503, ...

Propagation of a dicentric chromosome in plants has been shown to lead to structural gains and losses at the terminus of sister chromatids by repeated rounds of fusion-bridge breakage 32.

Abstract:A research group led by Professor SUZUKI Hiroaki from Faculty of Science and Engineering at Chuo University, graduate students YONEYAMA ...

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University of Arizona scientists have discovered that the loss of the Y chromosome in men's cells may make it more difficult ...

Chromosomes are cellular structures that contain the genetic material. A chromosome is comprised of a single DNA molecule that may be either circular or linear. The full complement of a cell s ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

The protocol for detecting candidates for gene loss and divergence in S. cerevisiae. nrify is a program in the SEALS package that is used to generate a nonredundant protein database.