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主要目标是比较波前手术，准分子激光原地角膜消除术（laser-assisted in-situ keratomileusis, LASIK）或激光光学角膜切削术（PRK）或准分子激光上皮下角膜磨镶术（laser epithelial keratomileusis, LASEK）与相应的传统手术在矫正成人术后未矫正视力、残留屈光不正和残留HOAs屈光不正方面的有效性和安全性。