The gastrointestinal wall is a significant site of first-pass metabolism for oral drugs, which is commonly associated with CYP450 and UGT enzymes. However, contributions of esterase activities in the ...

Hydrolysis occurs mostly in the liver and is one type of Phase I metabolism, which is mostly triggered by esterase and amidase. Esterase splits esters into an acid and an alcohol in a chemical ...

Use of a leukocyte esterase strip test may be a reliable tool to diagnose persistence of infection during second-stage revision procedures for periprosthetic joint infection, according to results.

Esterase metabolism and biotransformation to an inactive metabolite provide unique pharmacokinetic differences compared with other benzodiazepines. In May, the Centers for Medicare & Medicaid ...

The gastrointestinal wall is a significant site of first-pass metabolism for oral drugs, which is commonly associated with CYP450 and UGT enzymes. However, contributions of esterase activities in the ...