we now describe representative protocols for using this CDA approach for the 1 H NMR spectroscopic analysis of the enantiomeric excess of chiral diols. Dry a 10-ml round-bottomed flask before use ...

The vast majority of new small-molecule drug candidates are chiral, and methods must be identified for obtaining the desired enantiomer in high purity. A common approach ... 100% yield with 100% ...