The DBA/2 mouse model is an inbred mouse strain in which young DBA/2 mice are susceptible to audiogenic seizures, making them a model for epilepsy studies. This epilepsy model does re-capitulate ...

Using a range of genetically valid mouse models of epilepsy (or epilepsy risk), we employ state of the art home cage behavioral monitoring technology to understand how interictal behavior is directly ...

BMB-101 demonstrated a complete elimination of drop attacks in the DBA/2 mouse model - - The DBA/2 model is highly predictive of sudden unexpected death in epilepsy (SUDEP) - - Findings highlight ...

(RTTNews) - Bright Minds Biosciences (DRUG), Tuesday announced that BMB-101, its selective 5-HT2C Gq-biased agonist, completely abolished drop seizures in the DBA/2 mouse model of epilepsy.

We use a multidisciplinary approach that combines biochemistry, molecular biology, in vivo physiology, and behavioral paradigms to identify the cellular alterations that lead to memory deficits in ...