Enolase is essential, especially for organisms devoid of the Krebs cycle that depend solely on glycolysis for energy. Interestingly, enolase appears to serve a separate function in some organisms, in ...

More information: Fumiya Kasai et al, γ-enolase (ENO2) is methylated at the Nτ position of His-190 among enolase isozymes, The Journal of Biochemistry (2023).DOI: 10.1093/jb/mvad042 ...

It has been shown that glycolytic protein ENO1 (alpha-enolase) contributes to the pathogenesis of pulmonary hypertension ... restore the hypoxia-induced endothelial dysfunction and mitochondrial ...

Rheumatoid arthritis is one of the most common immune-mediated diseases. Its primary manifestation is inflammatory arthritis characterized by symmetric, polyarticular pain and swelling, typically ...

A Novel Enolase-1 Antibody Targets Multiple Interacting Players in the Tumor Microenvironment of Advanced Prostate Cancer Open Access. ... To investigate the antitumor mechanism of ENO1 mAb, we found ...

However, many of the mechanisms through which these metabolic activities are induced and how they ... Of these, the most substantially induced glycolytic gene was the neuron-specific isoform of ...

While the mechanisms through which ENO2 could modulate these distal metabolic pathways remain to be elucidated, there is increasing evidence for metabolites and the enzymes responsible for their ...

Novel therapy strategies are crucial for thyroid carcinoma treatment. It is increasingly important to clarify the mechanism of thyroid carcinoma progression. Several studies demonstrate that α-Enolase ...

Furthermore, we identified the increased expression of muscle specific glycolytic enzyme β-enolase through promoting the degradation of basal p53 is the underlying mechanism, which was dependent on ...