At 4 weeks pregnant, you might start to notice some pregnancy symptoms. Welcome to the beginning of the embryo stage. It’s ...

Establishment of an in vitro hepatocyte differentiation model (A-B)), of which human embryonic stem cells (ES) were induced to be differentiated into definitive endoderm (DE), liver progenitor (LP) ...

Pattern formation is the developmental process by which cells acquire different identities, depending on their relative spatial positions within the embryo. Pattern formation ensures that tissues ...

The abilities of TGF-β family proteins and Smad signalling to direct and redirect differentiation have been demonstrated in various vertebrate tissue systems, including in the immune and ...

Advances in stem cell biology and immune cell engineering bring diabetes cell therapies closer to reality. I n 2024, a woman ...

These can be maintained in an undifferentiated state and can differentiate into the three germ layers endoderm, ectoderm, and mesoderm. Embryonic stem cells are pluripotent cells, so we believe ...

1 Department of Clinical Genetics, Addenbrooke’s Hospital, Cambridge, UK 2 Department of Medicine, University of Cambridge, Addenbrooke’s Hospital Correspondence to: Dr S M Park Department of Clinical ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...