The strong shear stress altered the membrane lipid microdomain structure of endocardial cells, which activated mTORC2 and PKC and promoted Notch1 cleavage even in the absence of strong ligand ...

Cells can also send out packages called exosomes, lipid vesicles that bubble off from the cell membrane. But for about 20 ...

From his lab at the University of Houston College of Pharmacy Drug Discovery Institute, Mingfu Wu, associate professor, is ...

New hope offered by a pharmacy team for treating heart disease by sharing insights into the fundamental process of how the heart is formed in utero.

By use of the 3 slice orientations of the LV, the LV myocardial emission activity is segmented from any other adjacent emission activity. Next, the basal and apical limits are detected, and the ...

From his lab at the University of Houston College of Pharmacy Drug Discovery Institute, Mingfu Wu, associate professor, is offering new hope for treating heart disease by sharing his insights into the ...

这项发现不仅解开了困扰发育生物学界50年的"心脏形态发生之谜"，更揭示了细胞通讯的量子跃迁：在纳米尺度上，生命竟演化出堪比光纤网络的信号高速公路。想象未来医生通过修复这些微观管道治疗先天心脏病，或利用仿生纳米管实现心肌再生，此刻实验室里的小鼠心脏成像 ...

New findings on tunneling nanotube-like structures offer critical insights into heart formation, paving the way for innovative heart disease therapies.

Insights into the fundamental process of how the heart is formed offer new hope for treating heart disease. The findings ...

“Here we characterized Tunneling Nanotube-Like Structures (TNTLs), which we found physically connecting cardiomyocytes in myocardium to endocardial cells in endocardium,” reports Wu.