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Emodin has previously been reported to inhibit mechanical stress-induced HS inflammation. Here, we investigated the molecular mechanisms underlying the inhibitory effects of emodin on HS formation.
Emodin inhibited hypoxia injury in H9c2 cells Emodin exhibited no negative effect on viability of H9c2 cells at concentrations of 5, 10, and 15 μM, but cell viability was decreased by 0.82 times by ...
The dried rhizomes and roots of Rheum palmatum are widely used in China, Russia, and Arabia for the treatment of various diseases, with anthraquinone glycosides being the principal bioactive ...
A Cd(II)−Nd(III) nanocluster [Cd8Nd12L12(OAc)34(OH)6(H2O)2] (1) was constructed from the vanillin-type ligand 3-ethoxysalicylaldehyde (HL). It shows temperature-dependent NIR luminescence and is used ...
Herbalife Ltd. (NYSE: HLF), a premier health and wellness company, community and platform, today announced the Association of ...
芦荟大黄素 (Aloe-emodin)这种蒽醌类衍生物展现出令人惊喜的抗癌特性。在人类肝癌细胞系Hep3B中,它像精准的"分子开关"般激活AMP活化蛋白激酶 (AMPK),引发一系列连锁反应:先是促使微管相关蛋白轻链3 (LC3-II)和p62从细胞质"搬家"到线粒体,接着显著提升线粒体内PTEN诱导激酶1 (PINK1)和parkin的表达水平 ...
这种由NLRP3炎症小体触发、Caspase 1执行、GSDMD介导的新型程序性死亡方式,已成为神经保护研究的新靶点。 传统中药大黄活性成分大黄素 (Emodin)虽在心肌、肺等器官缺血再灌注损伤中显示抗焦亡作用,但其在脑缺血中的机制仍是未解之谜。
The Potyviridae family is one of the most economically significant groups of plant RNA viruses, causing severe yield losses in agriculturally important crops. Among the viral proteins encoded by ...
Herbalife's method was validated through a global multi-laboratory study involving eight independent laboratories. Each lab tested the same set of six aloe vera samples, including both raw ...
机器学习-微流控集成的一步法制备靶向脂质体策略溃疡性结肠炎(UC)作为全球性高发的慢性炎症性肠病,现有治疗手段存在疗效波动、副作用显著等局限,而天然药物大黄素(Emodin)虽具抗炎潜力,却因水溶性差、生物利用度低难以临床转化。与此同时,在纳米药物递送领域,脂质体作为理想的药物载体,其高效制备一直是制约临床 ...