Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system ...

(2) These cells are activated using anti-CD3/CD28 antibodies to stimulate their proliferation. (3) Genetic modification of the T cells is performed by inserting the CAR gene, enabling them to ...

recognizes specific tumor antigens through its chimeric antigen receptor (CAR), leading to enhanced phagocytosis of the tumor cells and concomitant presentation of tumor antigen to T cells for their ...

Autoantibodies and tumor-associated antigens (TAAs) are increasingly recognized as valuable tools in the early detection and diagnosis of various cancers. Autoantibodies are immune proteins that ...

State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, Nanjing 210093, China Department of Andrology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical ...

The product of this tumor suppressor gene, a 105-kilodalton polypeptide called pRB ... The pRB polypeptide is also a major target of several DNA virus oncoproteins (adenovirus E1A, SV40 T antigen, and ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to ...

The TP53 gene or its proteins are also referred to as tumor protein TP53, cellular tumor antigen TP53, phosphoprotein TP53, antigen NY-CO-13, or transformation-related protein 53. Learn more below ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to ...

We have generated membrane-associated T-cell engager molecules (MATEs) consisting of a CD3 binding domain as well as a Tat-PTD motif to facilitate their attachment to the surface of cells independent ...