Prolactin, a polypeptide hormone secreted by the anterior pituitary gland, plays a vital role in regulating several key ...

Prolactin is produced and released into the bloodstream by the pituitary gland. That production is usually slowed when the hypothalamus releases dopamine, a natural prolactin inhibitor.

When prolactin levels are abnormally high, it is due to conditions that either decrease the production of dopamine, increase the production of TRH, or both. This may be caused by diseases or disorders ...

Its production is controlled by other hormones called prolactin-inhibiting factors, which include dopamine, according to the Cleveland Clinic. Both men and women tend to have small amounts of ...

Dopamine agonist or levodopa can result in augmentation, a situation in which continued use of the medication actually worsens symptoms. With augmentation, the symptoms may occur earlier, affect other ...

On the other hand, more adverse effects of dopamine agonists have been ... hyperprolactinemia can have beyond the gonadal axis. Cooper said high prolactin levels can negatively affect bone and ...

Dopamine, a chemical in the brain, helps control prolactin production. Medications that affect dopamine levels may cause increased prolactin levels. Medications that may cause high prolactin ...

If you find out you have high prolactin levels or prolactinoma tumors, talk to your doctor right away about treatments. You can also ask about removing or reducing tumors. Dopamine agonists such ...

Many hormones, including prolactin, come from the pituitary gland. Dopamine, a neurotransmitter, and estrogen, a hormone, signal to the pituitary gland that it’s time to produce and distribute ...

The hypothalamic control of prolactin secretion is different from other anterior pituitary hormones, in that it is predominantly inhibitory, by means of dopamine from the tuberoinfundibular dopamine ...

It also influences functions outside of the CNS, such as the immune system and gut-brain axis. Like other substances in the body, dopamine promotes health when levels are within a certain range.

The following is a summary of “Hypothalamic-prolactin axis regulation in major depressed patients with suicidal behavior,” published in the May 2023 issue of Psychoneuroendocrinology by Duval et al.