This useful manuscript provides a newly curated database (termed AACDB) of antibody-antigens structural information ... All the sequence and structure files and the interacting data based on different ...

The usefulness of streptococcal antibody tests — anti-streptolysin O (ASO), anti-desoxyribonuclease B (anti-DNAse B), and anti-group A carbohydrate (A-antibody) — in differentiating rheumatic from non ...

Conclusions: The antibodies of subjects allergic to a bacterial antigen included IgE and IgG4 (particularly for males) compared with the almost exclusive IgG1 response of non-allergic subjects. The ...

We reveal mutation trajectories employing both CDR and framework (FW) mutations that present a vastly altered paratope to complement the distinctly different conformation presented by the flexible ...

A study in Chemistry A European Journal reveals that reduced MUC1 antigen density on gold nanoparticles still elicits potent ...

(A) 1AHW contains two copies of the same antigen and the same antibody. (B) In 6OGE, two different antibodies bind to distinct epitopes of the same antigen. (C) In 3BQU, an anti-idiotypic antibody ...

JNJ-79635322 shows favorable responses and manageable safety in BCMA/GPRC5D-naïve patients with relapsed/refractory multiple ...

Antibodies that react with self-molecules ... immune complexes Research is needed to clarify why certain antigens are targeted in different autoimmune diseases and how some antibodies activate ...

The partnership will use Debiopharm's AbYlink conjugation tech in combination with Alkyon’s modular antibody platform.

Find more information on the Altmetric Attention Score and how the score is calculated. Antibody orientation and its antigen binding efficiency at interface are of particular interest in many ...

Partnership combines AbTherx's proprietary Atlas™ Long CDR3 Technology with GPCR Therapeutics' deep expertise in GPCR biology to discover and develop antibodies for novel targets MOUNTAIN VIEW, ...

A landmark achievement occurred in 2017 with the first approval of chimeric antigen receptor T cell (CAR-T ... and dynamically emerging Research Topics, connecting communities of different sizes and ...