Endogenous antigens are processed in the cytoplasm and initiate cytotoxic T lymphocyte (CTL) activation. In contrast, exogenous antigens are degraded in the lysosome (or phagolysosome) of antigen ...

In this Review, we summarize studies that have used high-resolution imaging approaches to visualize antigen presentation to B cells in secondary lymphoid organs. These studies illustrate that ...

Recent advances of cancer immunotherapy have highlighted the critical role of T cells in cancer treatments by recognizing cancer-specific antigens. Neoantigens are one of the tumor-specific antigens, ...

of T cells to recognize a specific peptide, or antigen, found on tumor cells. There are many efforts underway to identify the most effective targets, and researchers have found some promising ...

Get Instant Summarized Text (Gist) A new class of small molecules, including fentomycin (Fento-1), selectively induces ferroptosis in aggressive, treatment-resistant cancer cells by targeting iron ...

We established prognostic nomograms incorporating prostate-specific membrane antigen (PSMA) positron emission tomography (PET) parameters standardised by Prostate Cancer Molecular Imaging Standardized ...

1Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut.

1Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.