By contrast, to generate DSS colitis models, mice orally receive DSS, causing death of epithelial cells, compromising barrier function and causing subsequent inflammation.

CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative ...

Further, they identify an antibody that reduces colitis severity and colonic tumor growth, ... reduces the severity of DSS colitis symptoms and suppresses colorectal tumor growth.

Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway. Cell Reports , 2022; 40 (5): 111158 DOI: 10.1016/j.celrep.2022.111158 Cite This Page : ...

Researchers from Ocean University of China and Qingdao Marine Science and Technology Center published data from a preclinical study that investigated the impact of the quinazolinone derivative MR-2938 ...

What is colitis? Colitis is the inflammation of the colon, also known as the large intestine. This inflammation is characterized by "swelling, irritation or damage to the colon’s inner lining ...

ICB treatment induces colitis-related indicators in DSS drinking mouse model. March 27, 2025. Researchers from Chinese Academy of Sciences detailed the creation of a new dextran sulfate sodium ...

How to manage ulcerative colitis and improve your gut health 04:23. Our gut is the key to much of our body's overall health, which is why diseases like ulcerative colitis can be so detrimental ...