RESULTS: Two intronic SNPs, rs680730 (in DSCAML1) and rs10129954 (in DPF3), were associated with the percent of normal sperm morphology in Chicago men (P = 0.017 and 0.023, respectively).

Using karyotyping (examining her chromosomes), they found several rare genetic variants, including some on DSCAML1—a gene associated with aging brain health, aging and cancer, heart disease ...

Using karyotyping (examining her chromosomes), they found several rare genetic variants, including some on DSCAML1—a gene associated with aging brain health, aging and cancer, heart disease ...

普通的大分子蛋白，通过分子克隆构建载体并在大肠杆菌中进行诱导表达获得重组蛋白，纯化鉴定后可直接作为免疫原。 小分子蛋白或化合物等分子量小，需要偶联载体对该分子进行改造才能使其成为具有免疫原性的抗原，常见偶联载体如BSA、OVA、HAS等。 选择 ...

Sixteen SNPs in 9 genes met the statistical cutoff for association with SVS. These were involved in extracellular matrix integrity (CHD23, CLDN14, SPTBN1), neuronal differentiation (DSCAML1), ...

Synaptic communication is an important process in the central nervous system that allows for the rapid and spatially specified transfer of signals. Neurons receive various synaptic inputs and generate ...

Zhang et al. deliver an important transcriptomic atlas of the human spinal cord, combining single-cell and spatial transcriptomics to unveil molecular insights. While convincingly overcoming Visium ...

Researchers found that deficiencies in the molecule DSCAML1, short for DS cell adhesion molecule like 1, can disrupt brain development and increase baseline levels of cortisol, which makes the ...

Deficiencies in the molecule called DSCAML1, short for DS cell adhesion molecule like 1, disrupt brain development and increase baseline levels of cortisol, making the primary stress hormone less able ...

Deficiencies in the molecule called DSCAML1, short for DS cell adhesion molecule like 1, disrupt brain development and increase baseline levels of cortisol, making the primary stress hormone less ...

By contrast, mouse DSCAML1 or Drosophila DSCAMs do not show similar patterns at the adhesion interfaces. These results suggest that DSCAMs might have different structural roles and mechanisms in ...