Chromosomes carry our basic genetic material. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Your DNA blueprint (genome) doesn't exist as ...

The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom In eukaryotes, the perfect duplication of the chromosomes is executed by ...

Priming of single stranded templates is essential for DNA replication. In recent years ... The rotational clash model advanced to explain this regulation in eukaryotic primases (Baranovskiy et al., ...

Chromosome duplication in eukaryotes is initiated from many origins of DNA replication on each chromosome, leading to the progression of DNA replication forks across the genome until fork convergence ...

Importantly, while other eukaryotes lack well-defined origins, they contain the same replication machinery as budding yeast. However, the global dynamics that underlie replication of chromosomes was ...

All eukaryotic cells ... outside of the subtelomeres in chromosome 2, only three were associated with detectable discrepancies between the simulation and the observed Pu-seq data, and the ...

Eukaryotic DNA replication occurs at many points within the chromosome, therefore replication forks meet and terminate at many points. DNA replication must be stopped or blocked for termination to ...

Before a cell can divide, it must duplicate its DNA. In eukaryotes – organisms such as animals and fungi, which store their DNA in the cell’s nucleus – DNA replication starts at specific sites in the ...

forks converge until all intervening DNA is unwound; any remaining gaps are filled and ligated; catenanes are removed; and replication proteins are unloaded. In eukaryotes, most termination sites ...