The Collection “DNA Replication and Replication ... A series of cryo-EM images offer structural information on the proofreading process, showing how DNA is transferred between the polymerase ...

At some point, RNA must have replicated itself before the evolutionary arrival of DNA and proteins, and now we might know how ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

Researchers demonstrated how Mycobacterium tuberculosis modifies its DNA and regulates both replication and gene activity through a reversible process known as ADP-ribosylation. This is the first ...

If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic instability and cancer. Researchers at UNIST and IBS have experimentally ...

In a study published in The EMBO Journal, researchers show how Mycobacterium TB uses a reversible process called ADP-ribosylation to modify its DNA and control both replication and gene activity.

“The structure reveals for the first time the mechanism underlying the strand exchange process during DNA repair via homologous ... from the individual images of more than 100,000 physical ...