its importance for the formation of ligatable ends during mtDNA replication. We demonstrate that inactivation of the exonuclease activity will increase strand-displacement activity, that is, DNA ...

To our knowledge, PHA-767491 is the first molecule that directly affects the mechanisms controlling initiation as opposed to elongation in DNA replication, and its activities suggest that Cdc7 ...

Researchers demonstrated how Mycobacterium tuberculosis modifies its DNA and regulates both replication and gene activity through a reversible process known as ADP-ribosylation. This is the first ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication ... found that when USP50 is absent during replication activity, cells attempted to use various ...

Cells use this process to regulate, or "license" the replication ... basic states of genomic DNA, the "euchromatin" state which is relatively loose and open for gene activity, and the ...