Witness the fascinating world of DNA replication brought to life through magnetic ball experiments. These magnetic games use a unique visual approach to demonstrate how the building blocks of life ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

[Editors' note: this paper was reviewed by Review Commons.] Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability. This feature ...

Version of Record: This is the final version of the article. The manuscript by Coquel et al. investigates the effects of BKC and IBC, two compounds found in Psoralea corylifolia in DNA replication and ...

DNA repair and replication stress responses enable cancer cells to maintain optimal genome plasticity and also allow them to survive treatment with chemotherapeutic agents. Furthermore, cancers ...

The study explores DNA damage and repair in neurons, which lack replication checkpoints due to their non-dividing nature. It reveals that DNA damage itself acts as a checkpoint, limiting genomic ...

DNA damage can result in the genetic sequence being misread and copied during cell division -- known as DNA replication -- and this introduces permanent mutations that can contribute to the ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides—whether to repair damaged tissue, replace old cells, or simply to help the ...

近期，哥本哈根大学诺和诺德基金会蛋白质研究中心的研究人员在npj Precision Oncology期刊上发表了一篇题为 “Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma” ...