Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

A new hereditary condition has been discovered that affects patients' ability to repair DNA—leaving them both at greater risk ...

To investigate how plants control EGT, the team focused on the DSB repair pathways—known entry points for organellar DNA. Using genetically engineered tobacco plants and a previously developed ...

The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA ...

To investigate how plants control EGT, the team focused on the DSB repair pathways — known entry points for organellar DNA. Using genetically engineered tobacco plants and a previously developed ...

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater ...

Drs Olga Brieieva and Martin Higgs discuss in vitro genomic models for predicting clinical resistance to PARP inhibitors for ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.