DNA microarray technology ... The 'decoder' approach described here complements this process by evaluating the equally important property of specificity: the tendency of a compound to inhibit ...

Wound repair is a complex biological process involving cell migration, proliferation and differentiation of multiple cell types. A number of growth factors, receptors, matrix molecules and ...

with complementary sequences in the target DNA. This process, known as DNA hybridization, allows the matching strands to bind together, making the pairing detectable through fluorescence.

It provides roughly 3,000 times more information than the DNA microarray method, which up until now has been used more widely. “Whole-genome sequencing gives us the chance to look at more data, which ...

However, these limitations are balanced by the advantages of an unbiased approach and the genome-wide evaluation of transcription. When combined with a pathway analysis procedure, RNA expression ...

The habeas corpus petition fails on its merits, court says Failed to show an unfair application of the testing procedure A death row inmate was unable to convince a federal appeals court that Texas’ ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by studying ancient and modern DNA.

Exome sequencing (ES) is commonly used to diagnose Mendelian disorders, which occur when pathogenic variant(s) in a gene are ...

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States Department of Chemistry, Duquesne University, Pittsburgh, Pennsylvania 15282, United States ...

May 13, 2025 — Researchers have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, powerful and environmentally benign chemistry. The new method ...

In standard procedures, binding is detected with Alexa Fluor 647-labeled streptavidin. The microarray facility will provide appropriate ‘anti-tag’ antibodies, as well as commercially available ...