Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged ...

Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

Researchers have mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage.

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

These proteins repair DNA damage from UV radiation using light. “They’re very good at using almost every single photon they catch,” says Thomas Lane at the German Electron Synchrotron (DESY).

In turn, experimentally induced suppression of NEAT1 levels delayed the DNA damage response, resulting in increased amounts of DNA damage. NEAT1 itself does not repair DNA damage. However, as the ...

The process to repair DNA goes into overtime when exposed to the deadly radiation to fix the damaged DNA. The findings are described in a study published April 12 in the journal Current Biology .

PARP1 then recruits repair proteins to the damage site by auto-PARylating itself. 2 If DNA is excessively damaged beyond repair, apoptotic pathways shut down DNA repair mechanisms, characterized by ...