Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

The G-loop acts like a landing pad for additional proteins. These proteins untie the G4 knot, break apart the G-loop and ...

The interior of the cell is super crowded with molecules ... of fundamental biochemical processes. "If this affects DNA strand separation, all protein interactions with DNA are also going to ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

Therefore, cells need tools to untie these knots quickly ... "With the help of proteins known for their role in DNA repair, RNA binds to the DNA strand opposite the G4 structure, forming a ...

As a postdoc, Komor found a way to achieve gene-editing with higher efficiencies and a lower incidence of indels by avoiding ...

A surprising solution to handle our ever increasing volume of data might be a substance operating at a much smaller scale – ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from organelles to the nucleus in plants. Disruption of DSBR increases the risk of ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the ...