Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and ...

The G-loop acts like a landing pad for additional proteins. These proteins untie the G4 knot, break apart the G-loop and ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

A new hereditary condition has been discovered that affects patients' ability to repair DNA—leaving them both at greater risk ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the ...