2019). The inflammatory cytokine IL-6 activates the Janus kinase (JAK) activation of signal transduction and transcription (STAT) signaling pathway, which inhibits expression of hepatocyte cytochrome ...

In this study, the protocol for liver cytochrome P450 (CYP) analysis from the native Brazilian fish Ancistrus multispinis was established. The microsome contamination by hemoglobin during the analysis ...

Pharmacokinetics, Dynamics and Metabolism (PDM), Department of Medicinal Chemistry, Pfizer Global Research and Development, 700 Chesterfield Parkway West T3A, Chesterfield, Missouri 63017, and ...

This review aims to provide a comprehensive perspective by contextualizing the historical and pharmacological significance of cannabinoids while focusing on their capacity to modulate the metabolic ...

Contributed by Rafael Radi; received August 8, 2022; accepted October 13, 2022; reviewed by Miguel De la Rosa and Mark Mamula ...

Find more information on the Altmetric Attention Score and how the score is calculated. Cytochrome P450 enzymes (P450s) are important in drug metabolism and have been linked to adverse drug reactions.