Defective CFTR protein, responsible for Cystic Fibrosis (CF), is highly expressed in pancreatic ductal epithelial cells (PDECs) but their impact on insulin secreting pancreatic islets is not fully ...

Cystic fibrosis represents one of the most common inherited genetic disorders affecting people of European descent, touching the lives of approximately 30,000 individuals in the United States alone.

Cystic fibrosis is inherited in an autosomal recessive fashion, which means a person has to inherit two abnormal genes in order for the disease to develop. Everyone inherits two CFTR genes, one ...

For cystic fibrosis, researchers were working blind: they had no protein and no location. This was to be a big test of new 'reverse genetics' techniques, in which a gene is found by searching for ...

Cystic fibrosis (CF) is an autosomal recessive condition ... and other organs throughout the body. CF is genetically inherited, which means it’s passed down through genes when sperm meets ...

Explore some of the key facts about cystic fibrosis—its causes, symptoms, diagnosis, treatment options, complications, and answers to frequently asked questions ...

Cystic fibrosis is an inherited genetic condition. It’s not contagious. To have the disease, you must inherit the faulty cystic fibrosis gene from both parents. The disease causes the mucus in ...

Inheritance The passing of characteristics ... Describe the symptoms of cystic fibrosis and how they are treated. Cystic fibrosis causes the build-up of sticky mucus in the gas exchange system ...

The Cystic Fibrosis (CF) Mouse Models Core at Case Western Reserve University (CWRU) produces, characterizes and exports various Cystic Fibrosis Mouse Models for CF research. In addition to providing ...