Cystic fibrosis represents one of the most common inherited genetic disorders affecting people of European descent, touching the lives of approximately 30,000 individuals in the United States alone.

A boy with cystic fibrosis is planning to complete a half marathon to raise money for a charity that supports people with the ...

in a gene are either inherited from one or both parents or are de novo. Examples of such disorders include cystic ... The United States Cystic Fibrosis Foundation released the first guideline on ...

Wright has cystic fibrosis, an inherited genetic lung disease, and wasn't diagnosed until age 54, and has sustained significant, irreversible lung damage. Terry Wright spent his childhood in ...

In many genetic diseases, a small error in the DNA code can have devastating effects. These errors, called nonsense mutations ...

More information: Eli Fritz McDonald et al, Proteostasis landscapes of cystic fibrosis variants reveal drug response vulnerability, Proceedings of the National Academy of Sciences (2025). DOI: 10. ...

The Department of Genetics and Genome Sciences is the proud home of the Cystic Fibrosis Research Center, the Institute for Glial Sciences, the Research Institute for Children's Health, the National ...

In epithelial cells, CFTR mediates Cl − secretion. Mutations in CFTR cause cystic fibrosis, whereas the activation of CFTR in the intestine causes secretory diarrhoea. Therefore the function and ...

Cystic fibrosis is a genetic disorder that affects roughly 40,000 Americans. The condition is caused by a mutation in the patient's cystic fibrosis transmembrane conductance regulator (CFTR) gene, ...

Dr. Mili Thakur is helping couples in West Michigan and across the country make their dreams a reality with her telehealth reproductive genetics consultation practice, Genome Ally.

Cystic fibrosis (CF) is a multi-organ genetic disease estimated to affect more than 100,000 ... By inhibiting ENaC function, it is possible to increase mucus hydration by keeping fluid in the airways.

When he was about 14, Pete Proimos learned a soul-crushing statistic about the cystic fibrosis he’d endured since birth: Patients back then didn’t live much past high school. “Should I go to ...