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Scientists say blocking bone marrow stromal cells from converting cystine into cysteine may provide a therapeutic approach against chronic lymphocytic leukemia (CLL), including drug-resistant disease.
Cysteine-elimination-induced browning and weight loss requires noradrenergic signaling. a, Tissue clearing and whole-brain c-Fos immunolabelling approach. b, Scheme of the thermosensory ...
Cysteamine acts as a cystine-depleting agent by converting cystine to cysteine and cysteine-cysteamine mixed disulfides and reduces corneal cystine crystal accumulation. Cystaran 0.44% ophthalmic ...
The glutathione-dependent system is one of the key systems regulating cellular redox balance, and thus cell fate. Cysteine, typically present in its oxidized form cystine in the extracellular ...
Cysteine restriction had other effects too; it triggered both the integrated stress response (ISR) and oxidative stress response (OSR). This simultaneous ISR and OSR pathway activation has only been ...
Previous investigations, in which cystine and cysteine were not separated, reported low plasma cystine values in cystinuria. 1,16 Brigham et al. 14 and Frimpter and his co-workers 10 each reported ...
The research team discovered that TRP14 (thioredoxin related protein of 14 kDa, also named TXNDC17 for thioredoxin domain containing 17) is the rate-limiting enzyme for intracellular cystine ...
Further Studies on the Distinctive Reaction for Cysteine and Cystine, Public Health Reports (1896-1970), Vol. 44, No. 24 (Jun. 14, 1929), pp. 1421-1428 Further Studies on the Distinctive Reaction for ...
Researchers have identified a substance in the blood that may be useful in predicting an individual's risk for heart disease. The substance is cystine, an oxidized form of the amino acid cysteine ...