This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

1Stanford University, Stanford, CA.

Eventually, the fluidity and permeability of cell membranes change, and cell structure and function are affected. Zhou Jing et al. discovered that the ROS scavenger, n-acetyl-l-cysteine (NAC), ...

Purpose: PEXS was first described in 1917, yet its etiology still needs clarification. An imbalance between oxidants and antioxidants plays a significant role. PEXS leads to various ocular ...

Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...

a Department of Surgery, University of Heidelberg, Heidelberg, Germany, b Department of Immunochemistry, German Cancer Research Center, Heidelberg, Germany Dr B Sido, Department of Surgery, University ...

School of Molecular and Cellular Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U.K. School of Molecular and Cellular Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U ...

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Here, we discuss the environmental and economic results. Expanding the analysis to other environmental impacts (Figure 4) shows that all of the assessed scenarios, except for the biogas BAU and the ...