Cyclophosphamide, a DNA-alkylating agent ... specific cellular responses — beyond the stereotypical apoptotic pathway — that render tumour-cell death immunogenic. These immunogenic ...

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...

Anifrolumab targets the type I interferon signalling pathway, which plays a role in the pathogenesis of lupus nephritis ... Patients were also required to discontinue investigational product treatment ...

The human cell lines SU-DHL4, OCI-Ly3, SU-DHL2, and U2932 were cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum, 100 U/mL penicillin, and 100 μg/mL streptomycin (Invitrogen, ...

Ann LaCasce, MD, MMSc, delved into some of the most recent advances in the lymphoma space, exploring how these new therapies ...

Over the last years, many biological markers emerged that act as an adjunct for the detection of early bladder cancer recurrence. Some of these markers had a proven better sensitivity and ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

There is therefore an urgent need for the development and testing of novel agents targeting pathways thought to be involved in the pathogenesis of breast cancer. Aberrant activation of the Ras/Raf ...