Another important aspect of corneal wound healing is the regeneration of the epithelial basement membrane (EBM). Studies have indicated that the successful regeneration of the EBM is critical for ...

Results: Amniotic membrane (AM) can function in the eye as a basement membrane substitute ... persistent epithelial defects of the cornea, and diseases that cause conjunctival scarring.

This requires healthy basement membrane and the creation of epithelial cell adhesion complexes to the underlying cornea and between adjacent epithelial cells. If these cellular adhesion complexes ...

Sutureless amniotic membrane (ProKera) was found to be partially or completely effective in corneal healing or symptomatic ... with more healthy looking epithelium in earlier stages of ...

The indication for insertion of ProKera was nonhealing corneal ulcers ... was recurrence of epithelial defect after the tarsorrhaphy was removed. Mean time to dissolution of membrane was 11.2 ...