Department of Chemical Engineering, Texas Tech University, P.O. Box 43121, Lubbock, Texas 79409-3121, United States ...

Figure 1 (reproduced from the original article by Mesecar and Koshland) shows the very small conformational changes in protein structure that cause differences in the catalytic constant of the ...

The two isomers of IgG4 differ in the disulfide bonding of hinge cysteines that are classically bonding the two H chains. However, these disulfide bonds are in flux, as they are a subject of reduction ...