CHICAGO -- Intracerebroventricular (ICV) delivery of bivalent CAR T-cells targeting EGFR and IL13Rα2 was feasible and ...

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its ...

Researchers are keen to incorporate fluorine into this molecule to optimise its properties but also study its conformational dynamics. Previously investigated method for creating fluorine-containing ...

Deionized (DI) water of Milli-Q grade was used in all sample preparation and analysis steps. For studying the conformational state of the zippers in different pH media with AFM and AGE, the 1× FOB of ...

Loop 6 was invisible in a previously published solution NMR structure of OmpG in n-dodecylphosphocholine micelles, presumably due to conformational exchange on an intermediate NMR time scale. Here we ...

Klebsiella pneumoniae is recognized by the CDC as a pathogen of urgent concern, due to the increase of multidrug-resistant strains.K. pneumoniae use type 1 pili tipped with the two-domain FimH adhesin ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute ...

Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Dual Hall of Fame trainer Roger Attfield goes over the physical and veterinary issues he's seen cause the most problems in ...