as a result of failed closure or formation of the embryonic neural tube. The most common and severe form is myelomeningocele (also termed open spina bifida or spina bifida aperta) (Fig.

investigators analyzed updated data on the effects of prenatal myelomeningocele closure on the need for placement of a cerebrospinal fluid (CSF) shunt within the first 12 months of life.

investigators analyzed updated data on the effects of prenatal myelomeningocele closure on the need for placement of a cerebrospinal fluid (CSF) shunt within the first 12 months of life.

Cranial ultrasound did not show the cisterna magna and fourth ventricle, consistent with an Arnold-Chiari malformation with myelomeningocele. The infant's ventricles were normal in size.

All three had undergone in utero closure of myelomeningocele at one institution. The preoperative evaluation and in utero treatment of the three patients have been described previously.

Most infants with myelomeningocele have hydrocephalus and require surgical treatment. There is currently little agreement among leading practitioners about the optimal timing of closure of the ...

Any birth defect involving incomplete closure of the spine results in ... nerves and meninges during the first month of pregnancy. Myelomeningocele is the most severe and the most common form ...

It is a neural tube defect. There are four main types of spina bifida: myelomeningocele spina bifida occulta closed neural tube defects meningocele Myelomeningocele is the most severe type.

(March 17 issue), 1 a randomized trial comparing the efficacy of prenatal repair of myelomeningocele with that of postnatal repair, Adzick et al. state that prenatal closure reduced the need for ...

Myelomeningocele (open spina bifida) is the most severe type of spina bifida ... in the meningomyelocele to be dissected from surrounding tissue so that it can drop into the spinal canal. The defect ...

Myelomeningocele is the most common and severe form of spina bifida, a neural tube defect in which the spinal vertebrae fail to develop normally during the first few weeks of gestation. It affects ...

(HealthDay)—The benefits of prenatal repair of myelomeningocele persist into school age, according to a study published online Feb. 8 in JAMA Pediatrics. Amy J. Houtrow, M.D., Ph.D., from the ...