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Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself DURHAM, N.C. -- Like its viral cousins, a somewhat parasitic DNA sequence called a ...
They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...
Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...
the extrachromosomal DNA (ecDNA) found in some cancer cells is not always split evenly. Lacking centromeres, these circular bits of DNA are often unevenly parceled to daughter cells. Some daughter ...
Prokaryotic cells have DNA, typically a single, circular molecule that contains all the genetic information necessary for the cell's functions and reproduction. Bacteria are single-celled organisms ...
"We know that cancers and tumor cells, they will carry a big load of the circular DNA," she told Live Science. "And that is, in some cases, actively driving the tumors." Rebecca Sohn is a ...
It had become supercoiled circular DNA again. And the EcoRI site had regenerated ... regulation of gene expression in mammalian cells, roles played by estrogen-related receptors in breast cancer, and ...
They hijack a little-known piece of the cell's DNA repair function to close ... The retrovirus HIV, which causes AIDS, is also known to form circular DNA. "I think these elements are the source ...